Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention

Alzheimer disease (AD) is multi-factorial and heterogeneous. Independent of the aetiology, this disease is characterized clinically by chronic and progressive dementia and histopathologically by neurofibrillary degeneration of abnormally hyperphosphorylated tau seen as intraneuronal neurofibrillary...

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Bibliographic Details
Main Authors: Iqbal, K, Grundke-Iqbal, I
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2008
Subjects:
Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139457/
https://ncbi.nlm.nih.gov/pubmed/18194444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00225.x
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