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Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease.
In Alzheimer disease, paired helical filaments accumulate in the neuron, and amyloid fibers are found in the extracellular space in the neuropil and brain vessels. Amyloid and paired helical filaments are morphologically distinct. Although messenger RNA that encodes the amyloid has also been shown i...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287017/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2649895/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.8.2853 |
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