Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

Leukemias with MLL gene translocations are a complication of primary cancer treatment with DNA topoisomerase II inhibitors. How early translocations appear during primary cancer treatment has not been investigated. We tracked the leukemic clone with an MLL gene translocation during neuroblastoma the...

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Main Authors: Megonigal, Maureen D., Cheung, Nai-Kong V., Rappaport, Eric F., Nowell, Peter C., Wilson, Robert B., Jones, Douglas H., Addya, Kathakali, Leonard, Debra G. B., Kushner, Brian H., Williams, Terence M., Lange, Beverly J., Felix, Carolyn A.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC16012/
https://ncbi.nlm.nih.gov/pubmed/10706619
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