Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

Leukemias with MLL gene translocations are a complication of primary cancer treatment with DNA topoisomerase II inhibitors. How early translocations appear during primary cancer treatment has not been investigated. We tracked the leukemic clone with an MLL gene translocation during neuroblastoma the...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Megonigal, Maureen D., Cheung, Nai-Kong V., Rappaport, Eric F., Nowell, Peter C., Wilson, Robert B., Jones, Douglas H., Addya, Kathakali, Leonard, Debra G. B., Kushner, Brian H., Williams, Terence M., Lange, Beverly J., Felix, Carolyn A.
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 2000
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050397097
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