Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors

Leukemias with MLL gene translocations are a complication of primary cancer treatment with DNA topoisomerase II inhibitors. How early translocations appear during primary cancer treatment has not been investigated. We tracked the leukemic clone with an MLL gene translocation during neuroblastoma the...

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הוצא לאור ב:	Proc Natl Acad Sci U S A
Principais autores:	Megonigal, Maureen D., Cheung, Nai-Kong V., Rappaport, Eric F., Nowell, Peter C., Wilson, Robert B., Jones, Douglas H., Addya, Kathakali, Leonard, Debra G. B., Kushner, Brian H., Williams, Terence M., Lange, Beverly J., Felix, Carolyn A.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	National Academy of Sciences 2000
נושאים:	Biological Sciences
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050397097
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