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The age incidence of chronic myeloid leukemia can be explained by a one-mutation model
Chronic myeloid leukemia (CML) is associated with the Philadelphia chromosome, which arises by a reciprocal translocation between chromosomes 9 and 22 and harbors the BCR-ABL fusion oncogene. It is unknown whether any other mutations are needed for the chronic phase of the disease. The CML incidence...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1595453/ https://ncbi.nlm.nih.gov/pubmed/17001000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607006103 |
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