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A Distant Upstream Locus Control Region Is Critical for Expression of the Kit Receptor Gene in Mast Cells

The Kit receptor tyrosine kinase functions in hematopoiesis, melanogenesis, and gametogenesis and in interstitial cells of Cajal. We previously identified two upstream hypersensitive site (HS) clusters in mast cells and melanocytes. Here we investigated the roles of these 5′ HS sequences in Kit expr...

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Detalhes bibliográficos
Main Authors: Berrozpe, Georgina, Agosti, Valter, Tucker, Christine, Blanpain, Cedric, Manova, Katia, Besmer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592758/
https://ncbi.nlm.nih.gov/pubmed/16847336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01854-05
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