Critical Role for Kit-mediated Src Kinase But Not PI 3-Kinase Signaling in Pro T and Pro B Cell Development

The Kit receptor functions in hematopoiesis, lymphocyte development, gastrointestinal tract motility, melanogenesis, and gametogenesis. To investigate the roles of different Kit signaling pathways in vivo, we have generated knock-in mice in which docking sites for PI 3-kinase (Kit(Y719)) or Src kina...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Agosti, Valter, Corbacioglu, Selim, Ehlers, Imke, Waskow, Claudia, Sommer, Gunhild, Berrozpe, Georgina, Kissel, Holger, Tucker, Christine M., Manova, Katia, Moore, Malcolm A.S., Rodewald, Hans-Reimer, Besmer, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2004
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212729/
https://ncbi.nlm.nih.gov/pubmed/15024050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031983
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge