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Critical Role for Kit-mediated Src Kinase But Not PI 3-Kinase Signaling in Pro T and Pro B Cell Development

The Kit receptor functions in hematopoiesis, lymphocyte development, gastrointestinal tract motility, melanogenesis, and gametogenesis. To investigate the roles of different Kit signaling pathways in vivo, we have generated knock-in mice in which docking sites for PI 3-kinase (Kit(Y719)) or Src kina...

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Detaylı Bibliyografya
Asıl Yazarlar: Agosti, Valter, Corbacioglu, Selim, Ehlers, Imke, Waskow, Claudia, Sommer, Gunhild, Berrozpe, Georgina, Kissel, Holger, Tucker, Christine M., Manova, Katia, Moore, Malcolm A.S., Rodewald, Hans-Reimer, Besmer, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212729/
https://ncbi.nlm.nih.gov/pubmed/15024050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031983
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