Critical Role for Kit-mediated Src Kinase But Not PI 3-Kinase Signaling in Pro T and Pro B Cell Development

The Kit receptor functions in hematopoiesis, lymphocyte development, gastrointestinal tract motility, melanogenesis, and gametogenesis. To investigate the roles of different Kit signaling pathways in vivo, we have generated knock-in mice in which docking sites for PI 3-kinase (Kit(Y719)) or Src kina...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Agosti, Valter, Corbacioglu, Selim, Ehlers, Imke, Waskow, Claudia, Sommer, Gunhild, Berrozpe, Georgina, Kissel, Holger, Tucker, Christine M., Manova, Katia, Moore, Malcolm A.S., Rodewald, Hans-Reimer, Besmer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212729/
https://ncbi.nlm.nih.gov/pubmed/15024050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031983
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados