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Kit ligand cytoplasmic domain is essential for basolateral sorting in vivo and has roles in spermatogenesis and hematopoiesis

Juxtamembrane signaling via the membrane growth factor KitL is critical for Kit mediated functions. KitL has a conserved cytoplasmic domain, and has been shown to possess a monomeric leucine dependent basolateral targeting signal. To investigate the consequences in vivo of impaired basolateral KitL...

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Detalhes bibliográficos
Main Authors: Deshpande, Shayu, Agosti, Valter, Manova, Katia, Moore, Malcolm A.S., Hardy, Matthew P., Besmer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812647/
https://ncbi.nlm.nih.gov/pubmed/19874813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.10.022
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