Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

Birt–Hogg–Dubé syndrome, a hamartoma disorder characterized by benign tumors of the hair follicle, lung cysts, and renal neoplasia, is caused by germ-line mutations in the BHD(FLCN) gene, which encodes a tumor-suppressor protein, folliculin (FLCN), with unknown function. The tumor-suppressor protein...

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Detaylı Bibliyografya
Asıl Yazarlar: Baba, Masaya, Hong, Seung-Beom, Sharma, Nirmala, Warren, Michelle B., Nickerson, Michael L., Iwamatsu, Akihiro, Esposito, Dominic, Gillette, William K., Hopkins, Ralph F., Hartley, James L., Furihata, Mutsuo, Oishi, Shinya, Zhen, Wei, Burke, Terrence R., Linehan, W. Marston, Schmidt, Laura S., Zbar, Berton
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592464/
https://ncbi.nlm.nih.gov/pubmed/17028174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603781103
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