Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

Birt–Hogg–Dubé syndrome, a hamartoma disorder characterized by benign tumors of the hair follicle, lung cysts, and renal neoplasia, is caused by germ-line mutations in the BHD(FLCN) gene, which encodes a tumor-suppressor protein, folliculin (FLCN), with unknown function. The tumor-suppressor protein...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Baba, Masaya, Hong, Seung-Beom, Sharma, Nirmala, Warren, Michelle B., Nickerson, Michael L., Iwamatsu, Akihiro, Esposito, Dominic, Gillette, William K., Hopkins, Ralph F., Hartley, James L., Furihata, Mutsuo, Oishi, Shinya, Zhen, Wei, Burke, Terrence R., Linehan, W. Marston, Schmidt, Laura S., Zbar, Berton
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2006
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592464/
https://ncbi.nlm.nih.gov/pubmed/17028174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603781103
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