Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein

Παρόμοια τεκμήρια

• The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain
  ανά: Lichtenthaler, Stefan F., κ.ά.
  Έκδοση: (2002)
• Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites
  ανά: Yan, Yan, κ.ά.
  Έκδοση: (2017)
• Transgenic Drosophila expressing human amyloid precursor protein show γ-secretase activity and a blistered-wing phenotype
  ανά: Fossgreen, Anke, κ.ά.
  Έκδοση: (1998)
• The Backbone Dynamics of the Amyloid Precursor Protein Transmembrane Helix Provides a Rationale for the Sequential Cleavage Mechanism of γ-Secretase
  ανά: Pester, Oxana, κ.ά.
  Έκδοση: (2013)
• γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP).
  ανά: Christian B Lessard, κ.ά.
  Έκδοση: (2015-01-01)