Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein

Những quyển sách tương tự

• The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain
  Bằng: Lichtenthaler, Stefan F., et al.
  Được phát hành: (2002)
• Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites
  Bằng: Yan, Yan, et al.
  Được phát hành: (2017)
• Transgenic Drosophila expressing human amyloid precursor protein show γ-secretase activity and a blistered-wing phenotype
  Bằng: Fossgreen, Anke, et al.
  Được phát hành: (1998)
• The Backbone Dynamics of the Amyloid Precursor Protein Transmembrane Helix Provides a Rationale for the Sequential Cleavage Mechanism of γ-Secretase
  Bằng: Pester, Oxana, et al.
  Được phát hành: (2013)
• γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP).
  Bằng: Christian B Lessard, et al.
  Được phát hành: (2015-01-01)