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Stable transduction of quiescent CD34(+)CD38(−) human hematopoietic cells by HIV-1-based lentiviral vectors

We compared the efficiency of transduction by an HIV-1-based lentiviral vector to that by a Moloney murine leukemia virus (MLV) retroviral vector, using stringent in vitro assays of primitive, quiescent human hematopoietic progenitor cells. Each construct contained the enhanced green fluorescent pro...

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Bibliographic Details
Main Authors: Case, Scott S., Price, Mary A., Jordan, Craig T., Yu, Xiao Jin, Wang, Lijun, Bauer, Gerhard, Haas, Dennis L., Xu, Dakun, Stripecke, Renata, Naldini, Luigi, Kohn, Donald B., Crooks, Gay M.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC15882/
https://ncbi.nlm.nih.gov/pubmed/10077624
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