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Towards a Clinically Relevant Lentiviral Transduction Protocol for Primary Human CD34(+) Hematopoietic Stem/Progenitor Cells
BACKGROUND: Hematopoietic stem cells (HSC), in particular mobilized peripheral blood stem cells, represent an attractive target for cell and gene therapy. Efficient gene delivery into these target cells without compromising self-renewal and multi-potency is crucial for the success of gene therapy. W...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714083/ https://ncbi.nlm.nih.gov/pubmed/19649289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006461 |
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