Anti-HMGB1 Neutralizing Antibody Ameliorates Gut Barrier Dysfunction and Improves Survival after Hemorrhagic Shock

Intestinal barrier dysfunction occurs following hemorrhagic shock and resuscitation (HS/R). High-mobility group B1 (HMGB1) has been shown to increase the permeability of Caco-2 human enterocyte-like epithelial monolayers in vitro. In this study, we found that serum concentrations of HMGB1 were highe...

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Detalhes bibliográficos
Main Authors: Yang, Runkuan, Harada, Tomoyuki, Mollen, Kevin P, Prince, Jose M, Levy, Ryan M, Englert, Joshua A, Gallowitsch-Puerta, Margot, Yang, LiHong, Yang, Huan, Tracey, Kevin J, Harbrecht, Brian G, Billiar, Timothy R, Fink, Mitchell P
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578769/
https://ncbi.nlm.nih.gov/pubmed/16953558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2006-00010.Yang
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