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The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

High-mobility group box 1 (HMGB1) is a nuclear factor that is released extracellularly as a late mediator of lethality in sepsis as well as after necrotic, but not apoptotic, death. Here we demonstrate that in contrast to the delayed role of HMGB1 in the systemic inflammation of sepsis, HMGB1 acts a...

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Detalhes bibliográficos
Main Authors: Tsung, Allan, Sahai, Rohit, Tanaka, Hiroyuki, Nakao, Atsunori, Fink, Mitchell P., Lotze, Michael T., Yang, Huan, Li, Jianhua, Tracey, Kevin J., Geller, David A., Billiar, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213120/
https://ncbi.nlm.nih.gov/pubmed/15795240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042614
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