Hepatocyte specific HMGB1 deletion worsens the injury in liver ischemia/reperfusion: A role for intracellular HMGB1 in cellular protection

High mobility group box-1 (HMGB1) is an abundant chromatin associated nuclear protein and released into the extracellular milieu during liver ischemia/reperfusion (I/R), signaling the activation of pro-inflammatory cascades. Since the intracellular function of HMGB1 during the sterile inflammation o...

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Bibliografiske detaljer
Main Authors: Huang, Hai, Nace, Gary W., McDonald, Kerry-Ann, Tai, Sheng, Klune, John R., Rosborough, Brian R., Ding, Qing, Loughran, Patricia, Zhu, Xiaorong, Beer-Stolz, Donna, Chang, Eugene B., Billiar, Timothy, Tsung, Allan
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999251/
https://ncbi.nlm.nih.gov/pubmed/24375466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26976
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