Interferon regulatory factor-2 is protective against hepatic ischemia-reperfusion injury

Interferon regulatory factor (IRF)-1 is a nuclear transcription factor that induces inflammatory cytokine mediators and contributes to hepatic ischemia-reperfusion (I/R) injury. No strategies to mitigate IRF1-mediated liver damage exist. IRF2 is a structurally similar endogenous protein that compete...

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Main Authors: Klune, John R., Dhupar, Rajeev, Kimura, Shoko, Ueki, Shinya, Cardinal, Jon, Nakao, Atsunori, Nace, Gary, Evankovich, John, Murase, Noriko, Tsung, Allan, Geller, David A.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
Assuntos:
Liver and Biliary Tract
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468551/
https://ncbi.nlm.nih.gov/pubmed/22744333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00050.2012
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