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A Ser/Thr cluster within the C-terminal domain of the rat prostaglandin receptor EP3α is essential for agonist-induced phosphorylation, desensitization and internalization
1. Two isoforms of the rat prostaglandin E(2) receptor, rEP3α-R and rEP3β-R, differ only in their C-terminal domain. To analyze the function of the rEP3-R C-terminal domain in agonist induced desensitization, a cluster of Ser/Thr residues in the C-terminal domain of the rEP3α-R was mutated to Ala an...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576232/ https://ncbi.nlm.nih.gov/pubmed/15937517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706282 |
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