A carregar...
Pentamidine reduces hERG expression to prolong the QT interval
1. Pentamidine, an antiprotozoal agent, has been traditionally known to cause QT prolongation and arrhythmias; however, its ionic mechanism has not been illustrated. 2. In a stable HEK-293 cell line, we observed a concentration-dependent inhibition of the hERG current with an IC(50) of 252 μM. 3. In...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576113/ https://ncbi.nlm.nih.gov/pubmed/15711592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706140 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|