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hERG-deficient human embryonic stem cell-derived cardiomyocytes for modelling QT prolongation
BACKGROUND: Long-QT syndrome type 2 (LQT2) is a common malignant hereditary arrhythmia. Due to the lack of suitable animal and human models, the pathogenesis of LQT2 caused by human ether-a-go-go-related gene (hERG) deficiency is still unclear. In this study, we generated an hERG-deficient human car...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Stem Cell Res Ther |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8103639/ https://ncbi.nlm.nih.gov/pubmed/33962658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02346-1 |
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