hERG-deficient human embryonic stem cell-derived cardiomyocytes for modelling QT prolongation

BACKGROUND: Long-QT syndrome type 2 (LQT2) is a common malignant hereditary arrhythmia. Due to the lack of suitable animal and human models, the pathogenesis of LQT2 caused by human ether-a-go-go-related gene (hERG) deficiency is still unclear. In this study, we generated an hERG-deficient human car...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Stem Cell Res Ther
Hlavní autoři: Chang, Yun, Li, Ya-nan, Bai, Rui, Wu, Fujian, Ma, Shuhong, Saleem, Amina, Zhang, Siyao, Jiang, Youxu, Dong, Tao, Guo, Tianwei, Hang, Chengwen, Lu, Wen-jing, Jiang, Hongfeng, Lan, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103639/
https://ncbi.nlm.nih.gov/pubmed/33962658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02346-1
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky