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G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal
1. Tolerance to opioids frequently follows repeated drug administration and affects the clinical utility of these analgesics. Studies in simple cellular systems have demonstrated that prolonged activation of opioid receptors produces homologous receptor desensitization by G-protein receptor kinase m...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574178/ https://ncbi.nlm.nih.gov/pubmed/14662727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705595 |
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