Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance

Release of endogenous dynorphin opioids within the spinal cord after partial sciatic nerve ligation (pSNL) is known to contribute to the neuropathic pain processes. Using a phosphoselective antibody [κ opioid receptor (KOR-P)] able to detect the serine 369 phosphorylated form of the KOR, we determin...

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Bibliografische gegevens
Hoofdauteurs: Xu, Mei, Petraschka, Michael, McLaughlin, Jay P., Westenbroek, Ruth E., Caron, Marc G., Lefkowitz, Robert J., Czyzyk, Traci A., Pintar, John E., Terman, Gregory W., Chavkin, Charles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2004
Onderwerpen:
Development/Plasticity/Repair
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376823/
https://ncbi.nlm.nih.gov/pubmed/15140929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5552-03.2004
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