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Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance

Release of endogenous dynorphin opioids within the spinal cord after partial sciatic nerve ligation (pSNL) is known to contribute to the neuropathic pain processes. Using a phosphoselective antibody [κ opioid receptor (KOR-P)] able to detect the serine 369 phosphorylated form of the KOR, we determin...

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Detalhes bibliográficos
Main Authors: Xu, Mei, Petraschka, Michael, McLaughlin, Jay P., Westenbroek, Ruth E., Caron, Marc G., Lefkowitz, Robert J., Czyzyk, Traci A., Pintar, John E., Terman, Gregory W., Chavkin, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376823/
https://ncbi.nlm.nih.gov/pubmed/15140929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5552-03.2004
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