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Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance

Release of endogenous dynorphin opioids within the spinal cord after partial sciatic nerve ligation (pSNL) is known to contribute to the neuropathic pain processes. Using a phosphoselective antibody [κ opioid receptor (KOR-P)] able to detect the serine 369 phosphorylated form of the KOR, we determin...

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主要な著者: Xu, Mei, Petraschka, Michael, McLaughlin, Jay P., Westenbroek, Ruth E., Caron, Marc G., Lefkowitz, Robert J., Czyzyk, Traci A., Pintar, John E., Terman, Gregory W., Chavkin, Charles
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2004
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376823/
https://ncbi.nlm.nih.gov/pubmed/15140929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5552-03.2004
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