Llwytho...

Effect of fentanyl on 5-HT efflux involves both opioid and 5-HT(1A) receptors

1. Fentanyl is a μ-opioid analgesic that might disinhibit 5-HT neurons and thus increase 5-HT efflux. However, fentanyl also binds to 5-HT(1A) receptors, and if it activates 5-HT(1A) somatodendritic autoreceptors, the resultant inhibition might offset opioid-mediated increases in 5-HT efflux. To tes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tao, Rui, Karnik, Meghana, Ma, Zhiyuan, Auerbach, Sidney B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573976/
https://ncbi.nlm.nih.gov/pubmed/12922937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705378
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!