Long-term Stress with Hyperglucocorticoidemia-induced Hepatic Steatosis with VLDL Overproduction Is Dependent on both 5-HT2 Receptor and 5-HT Synthesis in Liver

Hepatic triglycerides production and adipose lipolysis are pivotal for long-term stress (LTS) or hyperglucocorticoidemia-induced insulin resistance. 5-hydroxytryptamine (5-HT) has been demonstrated to induce hepatic lipid metabolic abnormality by activating mammalian target of rapamycin (mTOR). In p...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Fu, Jihua, Ma, Shaoxin, Li, Xin, An, Shanshan, Li, Tao, Guo, Keke, Lin, Min, Qu, Wei, Wang, Shanshan, Dong, Xinyue, Han, Xiaoyu, Fu, Ting, Huang, Xinping, Wang, Tianying, He, Siyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737678/
https://ncbi.nlm.nih.gov/pubmed/26884719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.13062
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