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A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells

1. Our previous studies revealed that the immunosuppressive agent, FTY720, mainly induces mitochondria-involved apoptosis in some types of cancer cells, since Bcl-2 overexpression prevents the FTY720-induction of apoptotic stimuli. Furthermore, FTY720 induces G0/G1 cell cycle arrest. The present stu...

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Detalhes bibliográficos
Main Authors: Matsuoka, Yumiko, Nagahara, Yukitoshi, Ikekita, Masahiko, Shinomiya, Takahisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573783/
https://ncbi.nlm.nih.gov/pubmed/12711631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705182
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