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T cell selective apoptosis by a novel immunosuppressant, FTY720, is closely regulated with Bcl-2
1. A novel immunosuppressant FTY720 caused a significant decrease in peripheral T lymphocytes, but not in B lymphocytes upon oral administration. This decrease was mainly a result of FTY720-induced apoptosis. In this study, we confirmed FTY720-induced T cell selective apoptosis using lymphoma cell l...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573588/ https://ncbi.nlm.nih.gov/pubmed/12429567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704970 |
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