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Up-regulation of protective neuronal MicroRNAs by FTY720 and novel FTY720-derivatives

In searching for Parkinson’s disease (PD) pharmacotherapies we began studying FTY720, a food and drug administration (FDA) approved drug. We also created derivatives, FTY720-C2 and FTY720-Mitoxy, and began assessing them. Here we treated dopaminergic MN9D cells with FTY720s then measured microRNA (m...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Vargas-Medrano, Javier, Yang, Barbara, Garza, Nathan T., Segura-Ulate, Ismael, Perez, Ruth G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952001/
https://ncbi.nlm.nih.gov/pubmed/30359694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2018.10.040
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