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An immunosuppressive agent, FTY720, increases intracellular concentration of calcium ion and induces apoptosis in HL-60.

We previously reported that FTY720 is an efficient inducer of apoptosis in lymphocytes and cultured cell lines. In the present study, HL-60 human promyerocytoma cells also induced apoptosis through in vitro treatment with the drug, demonstrating extensive DNA fragmentation 6 hr after incubation. The...

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Bibliografski detalji
Glavni autori: Shinomiya, T, Li, X K, Amemiya, H, Suzuki, S
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1363881/
https://ncbi.nlm.nih.gov/pubmed/9378500
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