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A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells
1. Our previous studies revealed that the immunosuppressive agent, FTY720, mainly induces mitochondria-involved apoptosis in some types of cancer cells, since Bcl-2 overexpression prevents the FTY720-induction of apoptotic stimuli. Furthermore, FTY720 induces G0/G1 cell cycle arrest. The present stu...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573783/ https://ncbi.nlm.nih.gov/pubmed/12711631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705182 |
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