Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics

1. Ethanol and nicotine are commonly coabused drugs. Cytochrome P450 2E1 (CYP2E1) metabolizes ethanol and bioactivates tobacco-derived procarcinogens. Ethanol and nicotine can induce hepatic CYP2E1 and we hypothesized that both centrally active drugs could also induce CYP2E1 within the brain. 2. Mal...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Howard, Lisa A, Miksys, Sharon, Hoffmann, Ewa, Mash, Deborah, Tyndale, Rachel F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2003
Konular:
Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573767/
https://ncbi.nlm.nih.gov/pubmed/12711639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705146
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller