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Chronic morphine induces up-regulation of the pro-apoptotic Fas receptor and down-regulation of the anti-apoptotic Bcl-2 oncoprotein in rat brain

1. This study was designed to assess the influence of activation and blockade of the endogenous opioid system in the brain on two key proteins involved in the regulation of programmed cell death: the pro-apoptotic Fas receptor and the anti-apoptotic Bcl-2 oncoprotein. 2. The acute treatment of rats...

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Detalhes bibliográficos
Main Authors: Boronat, M Assumpció, García-Fuster, M Julia, García-Sevilla, Jesús A
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573055/
https://ncbi.nlm.nih.gov/pubmed/11704646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704364
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