Up-regulation of fas and fasL pro-apoptotic genes expression in type 1 diabetes patients after autologous haematopoietic stem cell transplantation

Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by T cell-mediated destruction of pancreatic β cells, resulting in insulin deficiency and hyperglycaemia. Recent studies have described that apoptosis impairment during central and peripheral tolerance is involved in T1D pathogenesi...

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Bibliografiske detaljer
Main Authors: de Oliveira, G L V, Malmegrim, K C R, Ferreira, A F, Tognon, R, Kashima, S, Couri, C E B, Covas, D T, Voltarelli, J C, de Castro, F A
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2012
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390481/
https://ncbi.nlm.nih.gov/pubmed/22519592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04583.x
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