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Levels of pro-apoptotic regulator Bad and anti-apoptotic regulator Bcl-xL determine the type of the apoptotic logic gate

BACKGROUND: Apoptosis is a tightly regulated process: cellular survive-or-die decisions cannot be accidental and must be unambiguous. Since the suicide program may be initiated in response to numerous stress stimuli, signals transmitted through a number of checkpoints have to be eventually integrate...

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Detalhes bibliográficos
Main Authors: Bogdał, Marta N, Hat, Beata, Kochańczyk, Marek, Lipniacki, Tomasz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750306/
https://ncbi.nlm.nih.gov/pubmed/23883471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-67
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