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Comparison of membrane insertion pathways of the apoptotic regulator Bcl-xL and the diphtheria toxin T-domain

The diphtheria toxin T-domain and the apoptotic repressor Bcl-xL are membrane proteins that adopt their final topology by switching folds from a water-soluble to a membrane-inserted state. While the exact molecular mechanisms of this transition are not clearly understood in either case, the similari...

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Bibliografiske detaljer
Main Authors: Vargas-Uribe, Mauricio, Rodnin, Mykola V., Ladokhin, Alexey S.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882133/
https://ncbi.nlm.nih.gov/pubmed/24134052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400926k
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