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Comparison of membrane insertion pathways of the apoptotic regulator Bcl-xL and the diphtheria toxin T-domain
The diphtheria toxin T-domain and the apoptotic repressor Bcl-xL are membrane proteins that adopt their final topology by switching folds from a water-soluble to a membrane-inserted state. While the exact molecular mechanisms of this transition are not clearly understood in either case, the similari...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882133/ https://ncbi.nlm.nih.gov/pubmed/24134052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400926k |
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