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Membrane translocation assay based on proteolytic cleavage: Application to diphtheria toxin T domain

The function of diphtheria toxin translocation (T) domain is to transfer the catalytic domain across the endosomal membrane upon acidification. The goal of this study was to develop and apply an in vitro functional assay for T domain activity, suitable for investigation of structure-function relatio...

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Bibliografski detalji
Izdano u:Biochim Biophys Acta
Glavni autori: Rodnin, Mykola V., Ladokhin, Alexey S.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259893/
https://ncbi.nlm.nih.gov/pubmed/25291602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.09.013
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