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Membrane translocation assay based on proteolytic cleavage: Application to diphtheria toxin T domain
The function of diphtheria toxin translocation (T) domain is to transfer the catalytic domain across the endosomal membrane upon acidification. The goal of this study was to develop and apply an in vitro functional assay for T domain activity, suitable for investigation of structure-function relatio...
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| Gepubliceerd in: | Biochim Biophys Acta |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259893/ https://ncbi.nlm.nih.gov/pubmed/25291602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.09.013 |
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