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Attenuation of tolerance to opioid-induced antinociception and protection against morphine-induced decrease of neurofilament proteins by idazoxan and other I(2)-imidazoline ligands
1. Agmatine, the proposed endogenous ligand for imidazoline receptors, has been shown to attenuate tolerance to morphine-induced antinociception (Kolesnikov et al., 1996). The main aim of this study was to assess if idazoxan, an α(2)-adrenoceptor antagonist that also interacts with imidazoline recep...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565592/ https://ncbi.nlm.nih.gov/pubmed/9776358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702031 |
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