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Attenuation of tolerance to opioid-induced antinociception and protection against morphine-induced decrease of neurofilament proteins by idazoxan and other I(2)-imidazoline ligands

1. Agmatine, the proposed endogenous ligand for imidazoline receptors, has been shown to attenuate tolerance to morphine-induced antinociception (Kolesnikov et al., 1996). The main aim of this study was to assess if idazoxan, an α(2)-adrenoceptor antagonist that also interacts with imidazoline recep...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Boronat, M Assumpció, Olmos, Gabriel, García-Sevilla, Jesús A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565592/
https://ncbi.nlm.nih.gov/pubmed/9776358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702031
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