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Activation of I(2)-imidazoline receptors enhances supraspinal morphine analgesia in mice: a model to detect agonist and antagonist activities at these receptors

1. This work investigates the receptor acted upon by imidazoline compounds in the modulation of morphine analgesia. The effects of highly selective imidazoline ligands on the supraspinal antinociception induced by morphine in mice were determined. 2. Intracerebroventricular (i.c.v.) or subcutaneous...

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Detalhes bibliográficos
Main Authors: Sánchez-Blázquez, Pilar, Boronat, M Assumpció, Olmos, Gabriel, García-Sevilla, Jesús A, Garzón, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572044/
https://ncbi.nlm.nih.gov/pubmed/10781010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703294
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