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Sphingosine-1-phosphate reduces rat renal and mesenteric blood flow in vivo in a pertussis toxin-sensitive manner

1. Sphingolipids such as sphingosine-1-phosphate (SPP) and sphingosylphosphorylcholine constrict isolated rat intrarenal and mesenteric microvessels in vitro. The present study investigates their effects on the cardiovascular system in vivo in anaesthetized rats. 2. The animals were given intravenou...

詳細記述

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書誌詳細
主要な著者: Bischoff, Angela, Czyborra, Peter, Meyer zu Heringdorf, Dagmar, Jakobs, Karl H, Michel, Martin C
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572274/
https://ncbi.nlm.nih.gov/pubmed/10952678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703516
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