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Modulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity
1. Cholinergic airway constriction is functionally antagonized by agonist-induced constitutive nitric oxide synthase (cNOS)-derived nitric oxide (NO). Since cNOS and arginase, which hydrolyzes L-arginine to L-ornithine and urea, use L-arginine as a common substrate, competition between both enzymes...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572255/ https://ncbi.nlm.nih.gov/pubmed/10952667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703488 |
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