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Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma
BACKGROUND: Using guinea pig tracheal preparations, we have recently shown that endogenous arginase activity attenuates inhibitory nonadrenergic noncholinergic (iNANC) nerve-mediated airway smooth muscle relaxation by reducing nitric oxide (NO) production – due to competition with neuronal NO-syntha...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1363345/ https://ncbi.nlm.nih.gov/pubmed/16409620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-6 |
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