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Characterization of [(125)I]-SB-258585 binding to human recombinant and native 5-HT(6) receptors in rat, pig and human brain tissue
1. SB-258585 (4-Iodo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulphonamide) is a high affinity ligand at 5-HT(6) receptors. It displays over 100 fold selectivity for the 5-HT(6) receptor over all other 5-HT receptors tested so far. SB-258585 has been radiolabelled, to high specific ac...
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Autores principales: | , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2000
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572217/ https://ncbi.nlm.nih.gov/pubmed/10928963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703458 |
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