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Pharmacokinetic-pharmacodynamic modelling of the convulsant interaction between norfloxacin and biphenyl acetic acid in rats

1. Fluoroquinolones (FQs) are associated with a low incidence of central nervous system (CNS) side effects, possibly leading to convulsions, especially when co-administered with nonsteroidal anti-inflammatory drugs (NSAIDS). Although the in vivo pro-convulsant activity of NSAIDS is essentially unkno...

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Bibliografische gegevens
Hoofdauteurs: Marchand, Sandrine, Pariat, Claudine, Bouquet, Serge, Courtois, Philippe, Couet, William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572014/
https://ncbi.nlm.nih.gov/pubmed/10780965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703260
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