A New Approach for Early Assessment of the Epileptogenic Potential of Quinolones

The epileptogenic potential of pefloxacin and norfloxacin, two quinolone antibiotics, was investigated in vivo in three different animal species by measuring drug concentrations in cerebrospinal fluid (CSF), which is part of the biophase, at the onset of convulsions. Interestingly, the pefloxacin-to...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Delon, Annie, Pariat, Claudine, Courtois, Philippe, Bouquet, Serge, Couet, William
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9756792/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.10.2756
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