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A New Approach for Early Assessment of the Epileptogenic Potential of Quinolones

The epileptogenic potential of pefloxacin and norfloxacin, two quinolone antibiotics, was investigated in vivo in three different animal species by measuring drug concentrations in cerebrospinal fluid (CSF), which is part of the biophase, at the onset of convulsions. Interestingly, the pefloxacin-to...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Delon, Annie, Pariat, Claudine, Courtois, Philippe, Bouquet, Serge, Couet, William
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9756792/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.10.2756
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