A New Approach for Early Assessment of the Epileptogenic Potential of Quinolones

The epileptogenic potential of pefloxacin and norfloxacin, two quinolone antibiotics, was investigated in vivo in three different animal species by measuring drug concentrations in cerebrospinal fluid (CSF), which is part of the biophase, at the onset of convulsions. Interestingly, the pefloxacin-to...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Delon, Annie, Pariat, Claudine, Courtois, Philippe, Bouquet, Serge, Couet, William
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Materias:	Pharmacology
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9756792/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.10.2756
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