Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution

1. The blood glucose-lowering efficacy of rosiglitazone (RSG) and the mechanisms of associated weight gain were determined in dietary obese rats (DIOs). DIO and chow-fed rats received RSG 0.3–30 mg kg(−1) daily for 21 days. 2. In DIOs, plasma glucose and insulin concentrations were reduced by RSG at...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pickavance, L C, Tadayyon, M, Widdowson, P S, Buckingham, R E, Wilding, J P H
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571779/
https://ncbi.nlm.nih.gov/pubmed/10602338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702932
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados